At 22H30 Saturday night Netcare 911 responded to reports of a collision on Mouton Road in Roodepoort.
Reports from the scene indicate that the driver of a mini-bus taxi lost control resulting in a rollover.
Three people sustained injuries, one critically so.
The patient a female in her twenties required Advanced Life Support intervention to stabilise her.
The Fire and Rescue Services had to use the Jaws of Life to free her from the wreckage.
Due to the nature of the patients injuries, Netcare 2 a specialised helicopter ambulance was activated to airlift the patient to hospital for further treatment.
All necessary authorities were on scene.