At 13H48 Saturday afternoon Netcare 911 responded to reports of a structural fire in Rivonia.
Reports from the scene indicate that a fire had started in a shopping centre restuarant allegedly due to a gas bottle explosion.
On closer inspection most of the building had been gutted by the Fire.
Fire and Rescue Services managed to douse the flames.
A total of seven patients sustained injuries ranging from minor to moderate.
An adult male patient had sustained serious burn wounds and was treated on scene by Advanced life support paramedics.
Once stabilised all the patients were transported by various ambulance services to hospital.
Due to the nature of his injuries the Netcare 1 Specialised Helicopter Air Ambulance was activated to airlift him to a specialised facility for the care he required.
Circumstances leading up to the fire will be investigated by the relevant authorities.